PT-141 Peptide’s Origins and Evolution

What is PT-141?

Bremelanotide, or PT-141, is the generic name for a research peptide being examined for its potential application in aiding the improvement of sexual dysfunction.

The peptide hormone alpha-Melanocyte stimulating hormone, which is naturally generated in the body and induces melanogenesis, served as the basis for the development of PT-141, a synthetically synthesized variation of the tanning peptide Melanotan 2. To have its desired impact, MSH stimulates specific melanocortin receptors.

MSH significantly impacts all three areas: lipid metabolism, hunger, and libido. In this way, PT-141 has been demonstrated in tests to have libido-enhancing effects via activating the melanocortin receptors MC1R and MC4R without causing skin tanning.

As a result of melanogenesis-stimulating qualities, Melanotan 1 and Melanotan 2 have also been investigated as potential safeguards against the damaging effects of UV radiation from the sun.

PT-141’s Origins and Evolution

The Melanotan 2 Peptide served as the basis for PT-141, which was tested as a self-tanning lotion. Nine original 10 male volunteer test participants had unexpected sexual excitement and spontaneous erections while using Melanotan 2.

Palatin’s Phase 2B clinical study was complete for premenopausal women with FSD. Top-line findings and primary data analysis were expected to be released in the first part of the fourth quarter of 2012. Research has revealed that PT-141 is beneficial in treating sexual dysfunction in males (erectile dysfunction or impotence) and females (sexual arousal disorder). It does not enhance sexual desire via the circulatory system as Viagra, and similar substances do, but instead through the neurological system.

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Before opening, we advise momentarily centrifuging the vial to allow the contents to settle to the bottom. Concentrate to 0.1–1.0 mg/mL in sterile distilled water or an aqueous buffer containing 0.1% BSA. Aliquots of stock solutions may be kept indefinitely at -20 degrees Celsius. Experts should use Buffer solutions for further dilutions. These are indications for licensed professionals only; you should not use these substances unless you are a researcher working in a lab environment.


This lyophilized preparation may be stored at ambient temperature if protected from light, but long-term preservation requires placing the container in a freezer and using a desiccant. After reconstituting, researchers may keep the preparation for an extended period at room temperature (between 2 and 8 degrees Celsius). Divide the reconstituted preparation into usable aliquots, and keep it at -20 degrees Celsius for optimal stability. Try to keep things from constantly freezing and thawing.

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Buy PT-141

Biotech Peptides has built a strong customer support staff that monitors the sales process in real-time to ensure that all consumers have a positive experience before, during, and after making a purchase. The BP support staff always follows the procedure. Everyone on staff is eager to answer your questions, process your returns and replacements, and address any concerns you may have.

You may buy PT-141 peptide  here or shop for popular items like GHRP-2, CJC 1295, Ipamorelin, ACE-031, GHRP-2, Melanotan II, Fragment 176-191, and more on Biotech Peptides because of our commitment to quality. The only acceptable usage for the things supplied here is in the academic study!